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In the early stages of the disease, white bloodstream cells known as macrophages ingest the fatty materials and become a major constituent of the smooth, flaky plaques that narrow the artery and reduce blood flow. Pieces of the plaque can also break apart and lodge in the mind, leading to a stroke. Although this function for macrophages is more developed, there are still many unanswered queries about the involvement of other styles of immune cells, such as dendritic cells . Related StoriesHDL not so good in protecting females against atherosclerosis, study showsNegative influence of high-fat diet on red bloodstream cells may promote development of cardiovascular diseaseNew device may help identify high risk atherosclerotic plaquesIn the paper, the authors explain that, ‘The precise definition of the development and function of the immune cells in normal and diseased arteries is increasingly important.